The World In A Grain of Sand by KdT Ventures

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Podcast: Amylyx Pharmaceuticals

kdtvc.substack.com

Podcast: Amylyx Pharmaceuticals

a neuro biotech founded in the dorm room of two scrappy Brown undergrads

Rima Chakrabarti
,
Mack
, and
Patrick Malone
Apr 19, 2023
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Podcast: Amylyx Pharmaceuticals

kdtvc.substack.com

Unlike tech, in biotech we don't typically hear stories of multi-billion dollar companies getting started in garages or dorm rooms. Amylyx Pharmaceuticals, a neuro biotech founded in the dorm room of two scrappy Brown undergrads, is the exception. 

In our podcast The World in a Grain of Sand, we break down an S1 from a recent biotech IPO and share insights on the science, business models, and financials. This week, KdT Partners Mack and Rima dig into Amylyx Pharmaceuticals and discuss:

  • the mechanism of action of Amylyx’s lead disease-modifying asset, and competitive positioning relative to other treatments for neurodegeneration such as aducanumab

  • Amylyx’s capital efficiency, and reaching PhII trials without a single institutional investor

  • Amylyx’s unique engagement of ALS patients from the earliest days of the company, helping ensure a strong commercial launch of their ALS therapy

  • and more

Spotify and Apple podcast links:

Apple Podcast

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Podcast: Amylyx Pharmaceuticals

kdtvc.substack.com
A guest post by
Rima Chakrabarti
Former neurologist and company builder finding ways to make the world a better place
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